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All research overviewsRESEARCH OVERVIEW

What Is TB-500?

Last reviewed: 17 August 2026

TB-500 lyophilised reference material vial

TB-500 is a synthetic peptide corresponding to an active region of thymosin beta-4, a naturally occurring actin-sequestering protein. Research literature studies it as a tool compound for cell-migration and repair pathways.

Thymosin β4 fragmentActin-bindingPreclinical
Research use only · Not for human consumption · 18+. This page describes the published scientific record for laboratory and educational research. It is not medical advice and not a recommendation to administer this compound to humans or animals.

How is TB-500 classified?

It is described as a peptide fragment rather than a receptor agonist — its studied activity is protein-interaction based, centring on actin binding, not on a defined cell-surface receptor.

How is its mechanism studied?

  • G-actin sequestration and cytoskeletal turnover in cell systems.
  • Cell migration and endothelial models relevant to angiogenesis.
  • Inflammatory-signalling readouts in animal repair models.

What kind of research exists?

The thymosin beta-4 parent protein has a substantial cell-biology literature; the TB-500 fragment itself is studied mainly in preclinical and veterinary research contexts. Human controlled data is limited, and reviews say so plainly.

What is it studied alongside?

Frequently paired with BPC-157 in preclinical repair-model literature and in combination reference materials.

How does Neo Labs supply and handle it?

Lyophilised, sealed vial, batch COA on request against the lot number. Cold, light-protected storage.

Primary literature

We link live PubMed searches rather than a fixed citation list, so you always land on the current indexed record — including papers published after this page was reviewed.

The indexed literature for these compounds is predominantly preclinical. Citations are provided for scientific reference and do not imply any human-use indication.

Important

For research use only. Not for human or veterinary consumption. Neo Labs supplies this compound solely as a laboratory reference material and makes no therapeutic, medical or performance claims. Nothing on this page is medical advice.

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