How is Melanotan II classified?
A cyclic heptapeptide melanocortin agonist, described as non-selective because it engages MC1R, MC3R, MC4R and MC5R rather than a single subtype — the key distinction from PT-141, which is studied for central receptor activity.
How is its mechanism studied?
- MC1R signalling in melanocyte models, studied in pigmentation research.
- MC3R and MC4R engagement, studied in central appetite and behaviour models.
- Receptor-binding affinity panels used to characterise selectivity.
What kind of research exists?
Receptor pharmacology from the 1990s onward, animal models, and a case-report literature describing outcomes associated with unregulated non-research use. That case literature is an important part of the published record and is one reason this compound is supplied for laboratory use only.
What is it studied alongside?
PT-141 (bremelanotide), Melanotan I (afamelanotide) and α-MSH as the reference endogenous ligand.
How does Neo Labs supply and handle it?
Lyophilised powder, third-party tested, batch COA. Cold, dark storage; laboratory use only.

